Oryx feature comparison chart

Feature	OryxNano	Oryx4	Oryx8
Vapor Diffusion Drops
Vapor Diffusion Multiple drops per reservoir single Protein
Vapor Diffusion Multiple drops per reservoir 2 Proteins
Vapor Diffusion Multiple drops per reservoir 3 Proteins
Vapor Diffusion Microseed Matrix Screening
Vapor Diffusion Additive Experiments
Microbatch with automatic oiling
Microbatch Additive experiments
Microbatch Microseed Matrix Screening
Optimization
Microbatch 6D optimization grids
Microbatch optimization incomplete factorial designs (7-channel)
Tools
Fluidigm Filling

The Major Differences between
Oryx8, Oryx4, and OryxNano

• Oryx8 is the flagship Douglas Instruments protein crystallization robot.  It can set up sitting drop nanodrops down to 100 + 100 nl.  (The reservoirs must be predispensed by some other method such as a 12-channel pipette.)  Standard additive and screening experiments are included.  Microbatch-under-oil screens can be set up (also down to 100 + 100 nl), as well as optimization experiments using up to 7 ingredients with full pH control.  Optimization is mainly applied to microbatch, although sitting drop can also be used by filling the reservoirs with a constant solution.
   

• Oryx4 is the compact version of the product for those users who do not want to do optimization. It produces vapor diffusion drops from pre-dispensed reservoirs (including seeding and additive experiments) and it can do microbatch-under-oil screening. Oryx4 can be upgraded to Oryx8 if Optimization becomes a requirement.
   

• OryxNano is our latest robot designed specifically for sitting drop screening, including seeding experiments. OryxNano does not do optimization or (officially) microbatch.  It is more affordable than the other models and most, if not all, competitive offerings.
   

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