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Microseeding is a very powerful method of accurately controlling the number of crystals in a drop. Often when microseeding is used for screening
(random MMS microseeding) or optimization showers of small crystals form.
To control the number of crystals you can set up dilutions of the seed stock. However, you can end up doing many rounds of seeding - how can you find the best dilution as quickly as possible?
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The 'Additive Scatter' experiment can test up to 5 seed stocks against a 2D gradient, e.g. pH vs precipitant.
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Case Study using the 'Cross Matrix' experiment:
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To request a quote or demonstration please contact Hilary@douglas.co.uk.
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Visit our booth and pick up a microseeding toolkit containing everything you need to do a MMS Microseeding experiment including the Hampton seed bead and crystal crusher. |
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Recent citations of Douglas Instruments products |
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Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA
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Douglas Instruments
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