Set up Sitting Drop and Microbatch-Under-Oil experiments at the same time

Available at the press of one button!

        -  Two screening methods
        -  Up to 4 drop ratios
        -  Additives (e.g. seed stock)
Video of Combined Microbatch and Vapor Diffusion experiment
Video of Microbatch-Under-Oil Optimization Gradient experiment

Visit our booth at ACA, Denver for more information.

        -  20 µL of protein is enough for both methods (2x 96x 100+100 nL drops)
        -  Automatic oil dispensing onto aqueous drop. This give much more consistent drop size, shape and mixing

Advantages of the microbatch under oil technique include:

        -  Microbatch reduces skins on the drop surface.
        -  Microbatch conditions are easier to scale up.
        -  The rate of evaporation can be controlled by oil. (Paraffin gives slow evaporation, silicone gives rapid evaporation.) For optimization under oil pure paraffin oil can be used, which reduces evaporation to a minimum

Douglas Instruments Vapour Batch plates are available in Hydrophillic or Hydrophobic material. Hydrophillic are often the best option for screening. Hydrophobic are useful for some optimization experiments and low surface tension solutions.

To request a quote or demonstration please contact Hilary@douglas.co.uk.

For any technical or product support questions please contact Stefan@douglas.co.uk

For anything else please contact Info@douglas.co.uk

Douglas Instruments will be at the following meetings:

Visit our booth and pick up a Microseeding Tool Kit containing everything you need to do a MMS microseeding experiment. The kit includes:
     -  Hampton Research Seed Bead
     -  Hampton Research Crystal Crusher
     -  Instructions and advice for making a seed stock, and setting up an MMS experiment.
     -  References to papers about MMS microseeding and 'cross-seeding'.

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