1. Protein crystallization screening

    ▪ Minimal protein wasted (< 0.5 µL)

    ▪ Low consumable cost

    ▪ Only 10.0 µL required for a 96 well screen

    Information about Oryx8

    Protein crystallization screening

    ▪ Minimal protein wasted (< 0.5 µL)

    ▪ Low consumable cost

    ▪ Only 10.0 µL required for a 96 well screen

    Information about Oryx8
  2. Scaling-up

    ▪ Drop range from 100 nL to 8.0 µL or larger

    ▪ Vary drop ratio or seed volume

    ▪ Dispense sitting drop, microbatch or hanging drop

    Information about scaling-up

    Scaling-up

    ▪ Drop range from 100 nL to 8.0+ µL or larger

    ▪ Vary drop ratio or seed volume

    ▪ Dispense sitting drop, microbatch or hanging drop

    Click for more information
  3. Automatic Optimization

    ▪ Dispense concentration and pH gradients

    ▪ Multivariate experiment design

    ▪ Reservoir filling for optimization volumes up to 500 µL

    Information about optimization

    Automatic Optimization

    ▪ Dispense concentration and pH gradients

    ▪ Multivariate experiment design

    ▪ Reservoir filling for optimization volumes up to 500 µL

    Click for more information
  4. Seed stock for rMMS

    ▪ Screen with highly concentrated seedstock

    ▪ Cross seeding from homologous proteins

    ▪ Dispense down to 10 nL seed stock

    Information about rMMS

    Seed stock for rMMS

    ▪ Screen with highly concentrated seedstock

    ▪ Cross seeding from homologous proteins

    ▪ Dispense down to 10 nL seed stock

    Information about rMMS
Automatic Protein Crystallization Systems

Minimal protein wasted
10.0 μl protein required for a 96 well
screen (100+100 nl)

rMMS microseeding
Screen with un-diluted seed stock.
1.5 μl required for 96 wells

Efficient dispensing
5 - 9 minutes for a 96 well screen.
(Dependant on volume + viscosity)

Low consumable cost
Re-usable microtips for screening
and optimization

Microbatch-under-oil
With automatic oil dispensing.
drops down to 70+70 nl

24 Well hanging drop
Dispense to coversides
fill reservoirs for optimization


Conferences

Douglas Instruments is attending the following meetings:

ACA, Lombard, Illinois, USA
18 July - 23 July 2025

ECM, Lviv - Poznan, Ukraine - Poland
25 August - 29 August 2025

IUCr 2026, Calgary, Canada
11 August - 19 August 2026



Please contact us to request to join
the Douglas Instruments Automatic
Protein Crystallization Group

Click Here to visit the group

 

 

Minimal protein wasted
10.0 μl protein required for a 96 well
screen (100+100 nl)

rMMS microseeding
Screen with un-diluted seed stock.
1.5 μl required for 96 wells

Efficient dispensing
5 - 9 minutes for a 96 well screen.
(Dependant on volume + viscosity)

Low consumable cost
Re-usable microtips for screening
and optimization

Microbatch-under-oil
With automatic oil dispensing.
drops down to 70+70 nl

24 Well hanging drop
Dispense to coversides
fill reservoirs for optimization


Conferences

Douglas Instruments is attending the following meetings:

ACA, Lombard, Illinois, USA
18 July - 23 July 2025

ECM, Lviv - Poznan, Ukraine - Poland
25 August - 29 August 2025

IUCr 2026, Calgary, Canada
11 August - 19 August 2026



Please contact us to request to join
the Douglas Instruments Automatic
Protein Crystallization Group

Click Here to visit the group

 

 

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